9:58 AM - 10:23 AM

[2AW-09-3] Critical roles of FRS2beta for creating the cytokine-rich precancerous microenvironment for mammary tumorigenesis

〇Tatsunori Nishimura¹, Natsuko Kimura², Takahiko Murayama¹, Yukino Machida^2,3, Daisuke Iejima², Reiko Sakamoto⁴, Mizuki Yamamoto⁵, Naoki Itano⁶, Yusuke Inoue⁷, Masataka Ito⁸, Nobuaki Yoshida⁴, Jun-ichiro Inoue⁵, Kouichi Akashi⁹, Hideyuki Saya¹⁰, Koji Fujita¹¹, Masahiko Kuroda¹¹, Issay Kitabayashi¹², Arinobu Tojo², Noriko Gotoh¹ (1.Div. of Cancer Cell Biol., Cancer Res. Inst., Kanazawa Univ., 2.Div. of Mol. Therapy, Inst. of Med. Sci., Univ. of Tokyo, 3.Nip.Veter. and Life Sci. Univ., 4.Lab. of Dev. Genetics, Inst. of Med. Sci., Univ. of Tokyo, 5.Div. of Cellular and Mol. Bio., Inst. of Med. Sci., Univ. of Tokyo, 6.Dep. of Molecular Biosci., Faculty of Life Sci., Kyoto Sangyo University, , 7.Dep. of Diag. Radiol., Sch. of Med.,Kitasato Univ., 8.Dep. of Anat., National Def. Med. College, 9.Dep. of Medicine and Biosystemic Sci., Grad. Sch. of Med., Kyushu Univ., 10.Div. of Gene Regul., Insit. of Adv. Medical Res., Keio Univ., 11.Dep. of Mol. Path., Tokyo Medical Univ., 12.Div. of Hemat. Malignancy, Nat. Cancer Cent. Res. Inst.)

breast cancer, cancer stem cells, microenviroment