Repeat instability induced by a DNA polymerase delta proofreading domain mutation introduced using CRISPR/Cas9

Shinya Oda; kyoko Hidaka; Genki Hayashida; Ryosuke Fujikane; Masumi Hidaka; Teruhisa Tsuzuki; Yoshimichi Nakatsu

[2LBA-016] Repeat instability induced by a DNA polymerase delta proofreading domain mutation introduced using CRISPR/Cas9

〇Shinya Oda¹, kyoko Hidaka², Genki Hayashida³, Ryosuke Fujikane⁴, Masumi Hidaka⁴, Teruhisa Tsuzuki⁵, Yoshimichi Nakatsu⁵ (1.Clin. Res. Inst., Natl. Kyushu Cancer Ctr., 2.Ctr. Fundam. Ed., Kitakyushu Univ., 3.Grad. Sch. Syst. Life. Sci., Kyushu Univ., 4.Dept. Phys. Sci. Mol. Biol., Fukuoka Dent. Coll., 5.Dept. Med. Biophys. Radiat. Biol., Fac. Med., Kyushu Univ.)

mismatch repair, microsatellite instability, genome editing

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The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2LBA-016] Repeat instability induced by a DNA polymerase delta proofreading domain mutation introduced using CRISPR/Cas9

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