[2LBA-017] DNA polymerase theta is a key influencer of unique cancer mutational signatures

Taejoo Hwang³, Shelley Reh², Yerkin Dunbayev¹, Yubin Sung¹, Nikita Thapa¹, Kevin M. Mcbride², Semin Lee³, Richard D. Wood², 〇KEIICHI TAKATA^1,3 (1.Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea. , 2.Department of Epigenetics & Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center P.O. Box 389, Smithville, TX, 78957, USA. , 3.School of Life Science, UNIST, UNIST-Gil 50, Eonyang-eup, Ulju-gun, Ulsan, Republic of Korea.)

DNA double strand breaks , DNA polymerase theta , alternative end-joining