[2LBA-073] Mutant IDH1 triggers Oncogene-Induced Senescence via upregulation of p16INK4a

〇Takeshi Kamakura^1,2, Yonghui Jin^1,2, Sakura Tamaki^1,2, Makoto Watanabe³, Takeshi Okamoto⁴, Hiroyuki Yoshitomi^5,6, Junya Toguchida^1,2,6,7 (1.Dept. of Tissue Regeneration, IFLMS, Kyoto Univ., 2.Dept. of Growth and Differentiation, CiRA, Kyoto Univ., 3.Life Sci. Res. Center, Shimadzu Corp., 4.Japanese Red Cross Otsu Hospital, 5.Dept. of Immunity and Cell Biology, Grad. Sch. of Med., Kyoto Univ., 6.Dept. of Orthopaedic Surgery, Grad. Sch. of Med., Kyoto Univ., 7.Inst. for Adv. of a Clin. and Transl. Sci., Kyoto Univ. Hospital, Kyoto Univ.)

IDH, p16INK4a, OIS, iPS, Chondrosarcoma