The Molecular Biology Society of Japan

The 42nd Annual Meeting of the Molecular Biology Society of Japan

The 42nd Annual Meeting of the Molecular Biology Society of Japan

Dec 3, 2019 - Dec 6, 2019
Fukuoka International Congress Center・Fukuoka sunpalace hotel & hall・Marine Messe Fukuoka

[2P-0053] SMARCA4 deficiency sensitizes lung adenocarcinoma cells to ATR inhibitor by elevated intrinsic DNA replication stress and reversed fork destabilization

〇Kiminori Kurashima1, Hideto Kashiwagi1, Takayuki Yamashita2, Takashi Kohno3, Bunsyo Shiotani1 (1.Div. Cellular Signaling, Natl. Cancer Ctr. Res. Inst., 2.Lab. of Mol. Genet., IMCR, Gunma Univ., 3.Div. Genome Biol., Natl. Cancer Ctr. Res. Inst.)

replication stress, ATR inhibitor, SMARCA4, lung adenocarcinoma, biomarker

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