[2P-0092] AKT signaling promotes epigenetic reprogramming through transcriptional and metabolic shift during iPSC generation

〇Yoichi Sekita¹, Yuki Sugiura², Akari Matsumoto¹, Yuki Kawasaki³, Toshiaki Ito¹, Kazuya Akasaka¹, Terushi Yamazaki¹, Ryo Konno⁴, Toshinobu Nakamura⁵, Fumitoshi Ishino³, Yoshio Kodera^4,6, Takashi Kohda^3,7, Tohru Kimura¹ (1.Lab. of Stem Cell Biol., Dept. of Biosci., Kitasato Univ. Sch. of Sci., 2.Dept. of Biochem. & Integrative Med. Biol., Sch. of Med., Keio Univ., 3.Dept. of Epigenetics, Med. Res. Inst., TMDU, 4.Dept. of Phys., Kitasato Univ. Sch. of Sci., 5.Lab. of Epigenetic Regulation, Nagahama Inst. of Biosci. and Tech., 6.Cent. for Disease Proteomics, Kitasato Univ. Sch. of Sci., 7.Lab. of Embryol. & Genomics, Dept of Biotech., Univ. of Yamanashi)

エピジェネティクス, Aktシグナル, リプログラミング, 代謝