[2P-0099] Comprehensive DNA methylation analysis of imprinted DMRs in Sotos syndrome reveals IGF2 -DMR0 as a DNA methylation-dependent, P0 promoter-specific enhancer

〇Ken Higashimoto¹, Hidetaka Watanabe^1,2, Noriko Miyake³, Sumiyo Morita⁴, Takuro Horii⁴, Izuho Hatada⁴, Naomichi Matsumoto³, Hidenobu Soejima¹ (1.Div. of Mol. Genet. & Epigenet., Dept. of Biomol. Sci., Fac. of Med., Saga Univ., 2. Dept. of Plastic & Reconstructive Surgery, Saga Univ. Hosp., 3.Dept. of Hum. Genet., Yokohama City Univ. Grad. Sch. of Med., 4.Lab. of Genome Sci., Biosig. Genome Resource Ctr., Inst. for Mol. and Cell. Reg., Gunma Univ.)

Sotos症候群, NSD1, DNAメチル化, IGF2