[2P-0243(2AW-07-1)] Inhibition of B cell receptor-directed NFAT activation by MO2455 causing PAR accumulation

〇Takae Onodera^1,2, Yuka Sasaki^1,2, Fumiaki Kozumi^1,3, Kenji Matsuno⁴, Takeji Takamura⁵, Tatsu Shimoyama³, Kengo Inoue⁶, Mitsuko Masutani^1,2 (1.Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Div. Cellular Signaling, Natl. Cancer Ctr. Res. Inst., 3.Div. Clin. Res. Support, Komagome Hosp., 4.Dept. Chem. Life. Sci., Sch. Adv. Eng., Kogakuin Univ., 5.Fac. Eng., Kanagawa Inst. of Tech., 6.Pharma Valley Center)

PARG, B cell receptor, NFAT