[2P-0348] High Hes1 expression and resultant Ascl1 suppression regulate quiescent versus active neural stem cells in the adult mouse brain

〇Risa Sueda^1,2, Itaru Imayoshi^1,2,3,4,5, Yukiko Harima¹, Ryoichiro Kageyama^1,2,3,5,6 (1.Inst. for Frontier Life and Medical Sciences, Kyoto Univ, Kyoto, Japan, 2.Grad Sch Biostudies, Kyoto Univ, Kyoto, Japan, 3.Research Center for Dynamic Living Systems, Grad Sch Biostudies, Kyoto Univ, Kyoto, Japan, 4.Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology, Saitama, Japan, 5.Inst. for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, Japan, 6.Grad Sch Med, Kyoto University, Kyoto, Japan)

adult neural stem cell, Hes1, Ascl1, notch signaling, oscillatory expression