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[2PW-04-6(2P-0052)] Role of proofreading exonuclease activity of replicative polymerase epsilon in replication fork slowing at DNA damage

Masataka Tsuda1, Takuya Abe2, Toshiki Tsurimoto3, Takehiko Shibata2, Shunichi Takeda1, 〇Kouji Hirota1,2 (1.Dpt. of Radiation Genetics, Grad. Sch. of Med., Kyoto Univ., 2.Dpt. of Chem., Grad. Sch. of Scie., Tokyo Metropolitan Univ., 3.Dpt. of Biol., Sch. of Sci., Kyushu Univ.)

Polymerase epsilon, Proofreading exonuclease, Camptothecin, Top1cc, Double strand break (DSB)

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