[3P-0044(2PW-13-5)] Human rare disease caused by genetic mutation provides insights into structural rearrangement in GPCR

〇Yukiko Kurihara¹, Toru Ekimoto², Chris T. Gordon³, Taro Kitazawa¹, Ryo Sugiyama¹, Risa Kotani¹, Yasunobu Uchijima¹, Mitsunori Ikeguchi², Amiel Jeanne³, Hiroki Kurihara¹ (1.Dept. of Physiol. Chem. and Metab., Grad. Sch. of Med., Univ. of Tokyo , 2.Grad. Sch. of Med. Life Sci., Yokohama City Univ., 3.Institut Imagine)

GPCR, Endothelin A receptor, MD simulation