[3P-0191] Cytotoxic mechanism of excess polyamine through translational repression of specific proteins encoded by polyamine modulon

〇Sachi Iwasaki¹, Akihiko Sakamoto¹, Junpei Sahara², Gota Kawai ², Kaneyoshi Yamamoto³, Akira Ishihama³, Takeshi Uemura^4,5, Kazuei Igarashi^4,5, Keiko Kashiwagi¹, Yusuke Terui¹ (1.Fac. of Pharm., Chiba Inst. of Sci., 2.Fac. of Eng., Chiba Inst. of Tech., 3.Fac. of Biosci., Housei Univ., 4.Amine Pharm. Res. Inst., 5.Grad. Sch. of Pharm. Sci., Chiba Univ.)

polyamines, polyamine modulon, cytotoxicity, cell growth, cell viability