[3P-0442] Development of induced pluripotent stem cell model of bipolar disorder derived from an Okinawan pedigree with a potential genetic component

〇Gakuya Takamatsu^1,2, Kumiko Yanagi⁶, Yoko Manome⁵, Kae Koganebuchi⁴, Junsoku Lee¹, Kanako Toyama¹, Mutsumi Isa³, Kotaro Hattori^7,8, Tomoko Hayakawa⁹, Chikako Miyauchi Hara⁵, Minami Hasegawa⁵, Dimitar Dimirov¹⁰, Tomoyuki Takahashi¹⁰, Hiroshi Kunugi⁷, Tsuyoshi Kondo², Ryosuke Kimura³, Tadashi Kaname⁶, Hirotaka James Okano⁵, Masayuki Matsushita¹ (1.Dept. of Mol. and Cell. Physiology, Grad. Sch. of Med., Univ. of the Ryukyus, 2.Dept. of Neuropsychiatry, Grad. Sch. of Med., Univ. of the Ryukyus, 3.Dept. of Human Biol. and Anatomy, Grad. Sch. of Med., Univ. of the Ryukyus, 4.Res. Ctr. for Advanced Med. Sciences, Fac. of Med., Univ. of the Ryukyus, 5.Div. of Regenerative Med., Jikei Univ., 6.Dept. of Genome Med., Natl. Ctr. for Child Hlth. and Develop., 7.Dept. of Mental Disorder Research, Natl. Inst. of Neurosci., 8.Med. Genome Cente., Natl. Inst. of Neurosci., 9.Div. of Clin. Pharmacology, Dept. of Pharmacol., Jichi Med. Univ., 10.Cell. and Mol. Syn. Func. Uni., Okinawa Inst. of Sci. and Tech. Grad.)

iPS cell, bipolar disorder, psychiatry, neural induction, genome analysis