[3P-0490] Chondrocytes highly express CCN3 with age, and its overexpression promotes cartilage aging

〇Miho Kuwahara¹, Satoko Takeuchi², Sei Kondo¹, Shanqi Fu¹, Mitsuaki Ono³, Takayuki Furumatsu⁴, Eiji Nakata⁴, Masaharu Takigawa⁵, Satoshi Kubota¹, Takako Hattori¹ (1.Dept. of Biochem. Mol. Dent., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 2.Okayama U. Dent. Sch., 3.Dept. of Mol. Biol. and Biochem., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 4.Dept. of Orthop. Surg., Okayama U. Grad. Sch. of Med. Dent. and Pharm. Sci., 5.ARCOCS, Okayama U. Dent. Sch.)

CCN3 (NOV), 軟骨, 老化, SASP, 変形性関節症