[3P-0523] GREB1 induced by Wnt/β-catenin signal promotes development of hepatoblastoma by suppressing TGFβ signal

〇Koei Shinzawa¹, Shinji Matsumoto¹, Taku Yamamichi^1,2, Yuuya Kasahara³, Satoshi Nojima⁴, Takahiro Kodama⁵, Satoshi Obika³, Tetsuo Takehara⁵, Eiichi Morii⁴, Hiroomi Okuyama², Akira Kikuchi¹ (1.Dept. of Mol. Biol. and Biochem., Grad. Sch. of Med., Univ. of Osaka, 2.Dep. of Ped. Surg., Grad. Sch. of Med., Univ. of Osaka, 3.Dep. of Bioorg. Chem., Grad. Sch. of Pharm. Sci., Univ. of Osaka, 4.Dep. of Pathol., Grad. Sch. of Med., Univ. of Osaka, 5.Dep. of Gastroenterol. and Hepatol., Grad. Sch. of Med., Univ. of Osaka)

hepatoblastoma, Wnt signal, TGFβ signal, cancer model mouse