[3P-0556] Reverse genetics analysis of the NBS1 I171V variant as a candidate factor underlying the individual differences in radiosensitivity

〇Keita Tomioka^1,2, Silvia Natsuko Akutsu¹, Hiromi Yanagihara¹, Hiroshi Tauchi³, Takashi Yamamoto⁴, Masao Kobayashi², Yoshiki Kudo⁵, Tatsuo Miyamoto¹, Shinya Matsuura¹ (1.Dept. Genet. and Cell Biol., RIRBM, Hiroshima Univ., 2.Dept. Pediatr., Grad. Sch. of Biomed and Health Sci, Hiroshima Univ., 3.Dept. Biol Sci., Fac. Sci., Ibaraki Univ., 4.Dept. Mol Genet., Grad.Sch. of Integrated Sci. Life, Hiroshima Univ., 5.Dept. Obstet. and Gynecol, Grad. Sch. of Biomed and Health Sci, Hiroshima Univ.)

NBS1, genome editing, radiosensitivity