[4P-0262(3AW-10-1)] Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

〇Kyoko Chiba¹, Hironori Takahashi², Min Chen³, Hiroyuki Obinata⁴, Shogo Arai⁵, Koichi Hashimoto³, Toshiyuki Oda², Richard J. McKenney¹, Shinsuke Niwa⁴ (1.UC Davis, 2.Dept. of Anatomy and Struct. Biol., Grad. Sch. of Med. Sci., Univ. of Yamanashi, 3.Dept. of Sys. Info. Sci., Grad. Sch. of Info. Sci., Tohoku Univ., 4.FRIS, Tohoku Univ., 5.Dept. of Rbt., Grad. Sch. of Engr., Tohoku Univ.)

kinesin, axonal transport, C. elegans