[4P-0507] Attempt to analysis of murine skin aging by a novel model mouse indicating and eliminating senescent cells

〇Yuka Kamei¹, Koichiro Kawaguchi¹, Yuko Kotani⁴, Kazunari Matsuda², Tomoharu Yasuda³, Tomoji Mashimo⁴, Masataka Sugimoto^1,5, Mitsuo Maruyama^1,5 (1.Dept. of Mech. of Aging, NCGG, 2.R&D Dept., Daiichi Sankyo Healthcare, 3.Dept. of Immunol., Grad. Sch. of Med., Hiroshima Univ., 4.Inst. of Exp. Animal Sci., Grad. Sch. of Med., Osaka Univ., 5.Dept. of Aging Res., Grad. Sch. of Med., Nagoya Univ.)

cellular senescence, skin aging, Cdkn2a, SASP