2:15 PM - 2:33 PM

[4W-04-6] H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids

〇Kyosuke Nakamura^1,2, Giulia Saredi^1,3, Jordan R. Becker⁴, Benjamin M. Foster^5,6,7, Nhuong V. Nguyen^6,7, Tracey Beyer^1,2, Laura C. Cesa^1,2, Peter A. Faull⁶, Saulius Lukauskas^5,6, Thomas Frimurer⁸, Chapman J. Ross⁴, Till Bartke^5,6,7, Anja Groth^1,2 (1.BRIC, Univ. of Copenhagen, 2.CPR, Univ. of Copenhagen, 3.Univ. of Dundee, 4.Wellcome Centre For Human Genetics, 5.Helmholtz Zentrum Munchen, 6.MRC LMS, 7.ICS, Imperial College London, 8.Faculty of Health Sci., Univ. of Copenhagen)

homologous recombination, DNA double-strand break, BRCA1, BARD1, DNA repair