3:00 PM - 3:30 PM

[4W-14-5] Positive selection in ulcerative colitis by inflammatory pathway mutation

〇Nobuyuki Kakiuchi^1,2, Motoi Uchino ³, Takako Kihara⁴, Kotaro Akaki⁵, Yoshikage Inoue⁶, Satoshi Nagayama⁷, Akira Yokoyama⁸, Tomonori Hirano^1,2, Yasuhide Takeuchi^1,9, Yotaro Ochi¹, Yusuke Shiozawa¹, Keisuke Kataoka¹⁰, Masahiro M. Nakagawa¹, Akinori Yoda¹, Yasuhito Nanya¹, Hideki Makishima¹, Yuichi Shiraishi¹¹, Kenichi Chiba¹¹, Masashi Sanada¹², Hiroyuki Miyoshi¹³, Yoshiharu Sakai⁶, Takaki Sakurai⁹, Hironori Haga⁹, Seiichi Hirota⁴, Hiroki Ikeuchi³, Osamu Takeuchi⁵, Satoru Miyano¹¹, Hiroshi Seno², Seishi Ogawa¹ (1.Dept. of Pathology and Tumour Biology, Kyoto Univ., 2.Dept. of Gastroenterology and Hepatology, Kyoto Univ., 3.Dept. of Inflammatory Bowel Disease, Div. of Surgery, Hyogo Col. of Med., 4.Dept. of Surgical Pathology, Hyogo Col. of Med., 5.Dept. of Medical Chemistry, Grad. Sch. of Med., Kyoto Univ., 6.Dept. of Surgery, Kyoto Univ., 7.Dept. of Gastroenterological Surgery, Cancer Inst. Hosp., 8.Dept. of Clinical oncology, Kyoto Univ., 9.Dept. of Diagnostic Pathology, Kyoto Univ. Hosp., 10.Div. of Molecular Oncology, National Cancer Ctr. Research Inst., 11.Lab. of DNA information Analysis, Human Genome Ctr., Inst. of Medical Science, The Univ. of Tokyo,, 12.Dept. of Advanced Diagnosis, Clinical Research Ctr., Nagoya Medical Ctr., 13.Div. of Experimental Therapeutics, Kyoto Univ.)

Ulcerative colitis, colon cancer, chronic inflammation, positive selection, remodelling