[4P-0557(3AW-07-4)] Study on the effect of indole-3-acetic acid, a food protein-derived intestinal bacteria metabolite, on bile acid-induced fatty liver.

〇Kana Yuasa¹, Yuta Watanabe¹, Koichi Kurata², Hideaki Kawahara², Minako Imazu³, Kanako Matsunami³, Satoshi Ishizuka⁴, Hidehisa Shimizu¹ (1.Grad. Sch. of Nat. Sci. and Tec., Univ. of Shimane, 2.Grad. Sch. of Fac. of Lif. and Env. Sci., Univ. of Shimane, 3.Fac. of Lif. and Env. Sci., Univ. of Shimane, 4.Res. Fac. of Agr., Univ. of Hokkaido)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0558] Transcription factor NRF3 (NFE2L3) activates mTORC1 signal via amino acids uptake

〇Misato Tani¹, Shuhei Hirose¹, Hina Kitano², Tsuyoshi Waku², Akira Kobayashi^1,2 (1.Grad. Sch. of Life and Med. Sci., Doshisha Univ., 2.Fac. of Life and Med. Sci., Doshisha Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0559] S-allyl cysteine enhances testosterone production in mice and mouse testis derived I-10 cells

〇Md Masud Rana¹, Kota Shiozawa¹, Katsuyuki Mukai², Koichi Eguchi², Michio Komai¹, Hitoshi Shirakawa¹ (1.Lab. Nutrition, Grad. Sch. Agri. Sci., Tohoku Univ, 2.Daicel Co.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0560] Effectiveness of mouse secondary osteoporosis model to mouse postmenopausal osteoporosis model by ovariectomy.

〇TSUKASA TATSUMI¹, miduho Kajihara¹, Akiko Yonetani¹, Kentaro Yomogida¹ (1.Mukogawa women's univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0561] Light exposure induces energy storage in the peripheral tissue.

〇Taira Wada¹, Shuichi Takahashi¹, Shigeki Shimba¹ (1.Sch. of Pharm., Nihon Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0562] Renal cyst formation in Psp (spermatogenesis-related gene) KO mice starts at a young age

〇Tomoko Kagiya¹, Shunji itoh², Ikuji Hatamura² (1.Dept. of Med. Tech., Fac. of Health Sci., Kansai Univ. of Health Sci., 2.Dept. of Health Sci., Grad. Sch., Kansai Univ. of Health Sci.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0563] Discovery of constituents reducing visceral adiposity in Moringa oleifera, ‘the miracle tree’.

〇Izumi Matsuoka¹, Kanae Hata ¹, Liqing Zang ¹, Hiroko Nakayama ¹, Norihiro Nishimura ¹, Hirotaka Katsuzaki², Yasuhito Shimada ^3,4,5, Youngil Kim⁶, Seiji Shu ⁶, Lekh Rah Juneja⁶ (1.Mie Univ. Grad. Sch, Regional Innov., 2.Dept. of life Sci., Grad. Sch. of Bio., Mie Univ., 3.Dept. of Pharmacol., Mie Univ. Grad. Sch. Med., 4.Mie Univ. Zebrafish. Screen. Cent., 5.Dept. Bioinfo., Mie Univ. Ad. Sci. Res., 6.Rohto Co., Ltd)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0564] How does mutation located far from both binding sites and active residue affect to enzyme? Investigation of vitamin K epoxide reductase by docking simulation and molecular dynamics

〇Kazuki Takeda¹, Yoshinori Ikenaka^1,2, Denis Fourches³, Kazuyuki D. Tanaka⁴, Shouta M.M. Nakayama¹, Tsutomu Tanikawa⁴, Dhoha Triki³, Xinhao Li³, Mayumi Ishizuka¹ (1.Lab. of Tox., Grad. Sch. of Vet. Med., Univ. of Hokkaido, 2.Water. Res. Gr.Unit for Env. Sci. & Manag., North-West Univ., 3.Dept. of Chem., NC St. Univ., 4.Tech. Lab., Ikari Shodoku CO. Ltd.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0565] Spermine synthesis inhibitor blocks 25-hydroxycholesterol-induced- apoptosis via SREBP2 upregulation in colorectal cancer cell spheroids

Miku Kakimoto¹, Hideya Yamamoto¹, 〇Arowu Tanaka¹ (1.Dept. of Life Sci., Sch. of Pharm., Yasuda W. Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[4P-0566] Lipid Metabolome Analysis to Elucidate the Pathophysiology of Diabetic Nephropathy

〇Mikiyasu Taguchi¹, Yuto Goto², Makoto Arita³, Yoshiro Saito⁴, Noriko Noguchi¹ (1.Sys. Life Sci. Lab., Grad. Sch. of Life & Med. Sci., Doshisha Univ., 2.Sys. Life Sci. Lab., Life & Med. Sci., Doshisha Univ., 3.Lab. for Metabolomics, RIKEN-IMS, 4.Grad. Sch. of Sci., Tohoku Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan