[1PW-12-2(3P-0583)] Generation and characterization of model mice carrying a pathogenic mtDNA mutation

〇Haruna Tani¹, Kaori Ishikawa^1,2, Jun-Ichi Hayashi³, Kazuto Nakada^1,2 (1.Grad. Sch. Life and Env. Sci., Univ. of Tsukuba , 2.Faculty Life and Env. Sci., Univ. of Tsukuba , 3.TARA, Univ. of Tsukuba)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:12 PM - 4:28 PM

[1PW-12-3(1P-0194)] Mitochondrial Lon protease is a gatekeeper for proteins newly imported into the matrix

〇Yuichi Matsushima¹, Kazuya Takahashi¹, Song Yue¹, Masamune Aihara¹, Daiki Setoyama¹, Takeshi Uchiumi¹, Dongchon Kang¹ (1.Dept. of Clin. Chem. & Lab. Med., Grad. Suh. of Med. Sci., Kyushu Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:28 PM - 4:44 PM

[1PW-12-4] The role of mitophagy-receptor proteins in mitophagy

〇Shun-Ichi Yamashita¹, David C. Chan², Tomotake Kanki¹ (1.Dept. of Cell. Phys., Niigata Univ. Grad. Sch. of Med. and Dent. Sci., 2.Div. of Biol. and Biol. Eng., Carifornia Inst. Tech.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:44 PM - 5:09 PM

[1PW-12-5(3P-0395)] Two novel sperm-specific polypeptides cooperatively regulate the VDAC function and sperm development

〇Shintaro Mise¹, Akinobu Matsumoto¹, Kazuya Ichihara¹, Hideyuki Shimizu¹, Masatomo Takahashi², Yoshihiro Izumi², Takeshi Bamba², Haruhiko Miyata³, Keisuke Shimada³, Masahito Ikawa³, Keiichi I. Nakayama¹ (1.Division of Cell Biology, MIB, Kyushu University, 2.Division of Metabolomics, MIB, Kyushu University, 3.Department of Experimental Genome Research, RIMD, Osaka University)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 5:09 PM - 5:25 PM

[1PW-12-6] Ectopic dsDNA of mitochondrial origin induces neurodegeneration

〇Hideaki Matsui¹ (1.Dept. of Neurosci Disease., Inst. Res. Promotion, Niigata Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 5:25 PM - 5:50 PM

[1PW-12-7] Mitochondrial-mediated antiviral innate immunity

〇Takumi Koshiba¹ (1.Dept. of Chem., Faculty of Sci., Fukuoka Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 5:50 PM - 6:15 PM

[1PW-13-1] DNA replication stress and regulation of DNA replication in mammalian pluripotent stem cells

Yasunao Kamikawa¹, Mai Naganuma¹, 〇Tomomi Tsubouchi¹ (1.National Institute for Basic Biology)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 3:45 PM - 4:05 PM

[1PW-13-2] DNA topoisomerase 1(Top1) contributes to DNA breaks under the regulation of AID in immunoglobulin gene diversification

〇Maki Kobayashi¹, Tasuku Honjo^1,2 (1.Dept. of Immunology and Genomic Med., Grad.Sch. of Med., Kyoto Univ., 2.KUIAS, Kyoto Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:05 PM - 4:25 PM

[1PW-13-3] Autophagy protects genome from replication stress for tumor suppression

〇Tsuyoshi Kawabata^1,4, Rei Unno², Tadashi Yamamuro⁴, Shun Kageyama³, Yoshinobu Ichimura³, Tao-Sheng Li¹, Takahiro Yasui², Masaaki Komatsu³, Tamotsu Yoshimori⁴ (1.ABDI, Nagasaki Univ., 2.Dept. of Nephro-Urology, Nagoya City Univ. Grad. Sch. of Med., 3.Dept. of Physiol., Juntendo Univ., Grad. Sch. of Med., 4.Dept. of Genet., Osaka Univ., Grad. Sch. of Med.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:25 PM - 4:45 PM

[1PW-13-4(2P-0064)] Disruption of SLFN11 gene prevents stalled fork degradation and results in phenotypic reversal in Fanconi anemia cells

Yusuke Okamoto¹, Yasuko Tenpaku ¹, Ayako L. Mochizuki¹, Masako Abe¹, 〇Minoru Takata¹ (1.Lab of DNA damage signal., RBC, Grad Sch of Biostudies, Kyoto Univ)

The 42nd Annual Meeting of the Molecular Biology Society of Japan |Tue. Dec 3, 2019 4:45 PM - 5:00 PM