[1LBA-073] An efficient method for creating and maintaining lethal mutant mice using inversion chromosome in C3H/HeJJcl strain identified via next-generation sequencing

○Takahisa Sasaki¹, Satoru Iwata^2,3,4, Miki Nagahara², Takashi Iwamoto^1,2,3 (1.Dept of Biomedical Sciences, Chubu Univ. Grad School of Life and Health Sciences, Kasugai, Japan, 2.Center for Education in Laboratory Animal Research, Chubu univ, Kasugai, Japan, 3.Dept of Biomedical Sciences, College of Life and Health Sciences, Chubu Univ, Kasugai, Japan, 4.College of Bioscience and Biotechnology, Chubu Univ, Kasugai, Japan)

CRISPR-Cas9, chromosomal inversion, lethal mutation, electroporation