[1P-0136] GALECTIN-3 BINDING TO T ANTIGEN DIRECTLY MODULATES WNT SIGNALING VIA FRIZZLED-5 ENDOCYTOSIS IN MOUSE EMBRYONIC STEM CELLS

〇Federico Pecori¹、Yoshihiro Akimoto²、Hisatoshi Hanamatsu³、Jun-ichi Furukawa³、Yasuro Shinohara⁴、Yuzuru Ikehara⁵、Shoko Nishihara^1,6 (1.Laboratory of Cell Biology, Department of Bioinformatics, Graduate School of Engineering, Soka University, 1-236 Tangi-machi, Hachioji, Tokyo 192-8577, Japan、2.Department of Anatomy, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan、3.Department of Advanced clinical glycobiology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo 060-8638, Japan、4.Department of Pharmacy, Kinjo Gakuin University, 2-1723 Omori, Moriyama-ku, Nagoya, Aichi 463-8521, Japan、5.Department of Molecular and Tumor Pathology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan、6.Glycan & Life System Integration Center (GaLSIC), Faculty of Science and Engineering, Soka University, 1-236 Tangi-machi, Hachioji, Tokyo 192-8577, Japan)

Wnt signaling pathway、C1GalT1、Glycosylation、Galectins、Pluripotency