The Molecular Biology Society of Japan

[1P-0382] Studies on the fully human antibody-producing mice (3): Analysis of in vitro efficacy of fully human monoclonal antibodies against EpCAM

○Naomi Miyake1, Yasuyuki Satofuka2, Takasi Moriwaki1,2, Satoshi Abe5, Hiroshi Tanaka5, Kayoko Morimoto5, Kunitaro Yamazaki3, Genki Hichiwa4, Yayan Wang1, Mitsuo Oshimura5, Takeshi Fukuhara6, Yasuhiro Kazuki1,2,3 (1.Dept. of Life Sci., Sch. of Med., Univ. of Tottori, 2.CERC, Univ. of Tottori, 3.Dept. of Reg. Med. Biofunc., Grad. Sch. of Med. Sci., Univ. of Tottori, 4.Dept. of Gen and Cell, Med. sci, Univ. of Tottori, 5.Trans Chromosomics Inc., 6.Dept. of Neurlogy, Univ. of Juntendo)

Fully human antibody-producing mice, Anti-EpCAM monoclonal antibody, Internalization, Antigen-drug conjugate

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