[2P-0040] Structural bases for the degradation selectivity of C2H2 zinc finger by thalidomide metabolite

○Hirotake Furihata¹, Satoshi Yamanaka², Toshiaki Honda³, Norio Shibata³, Masaru Tanokura¹, Tatsuya Sawasaki², Takuya Miyakawa¹ (1.Dept. of Appl. Life Chem., Grad. Sch. of Agri. and Life Sci., Univ. of Tokyo, 2.PROS., Univ. of Ehime, 3.Dept. of Eng.,Grad. Sch. of Eng., Univ. of Meikou)

Thalidomide, IMiDs, Celebron, C2H2 zinc finger, E3-ubiquitin ligase