[2P-0069] Programmable RNA knockdown using CRISPR-Cas13a and therapeutic target for ALK-rearranged lung cancer

○Mr. Saifullah¹, Sakari Matomo¹, Takeshi Suzuki^3,4, Toshifumi Tsukahara^1,2 (1.Area of Bioscience and Biotechnology, School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan, 2.Division of Transdisciplinary Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi city, Ishikawa 923-1292, Japan, 3.Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Ishikawa, Japan, 4.Molecular Therapeutic Target Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kamuma-cho, Kanazawa 920-1192, Japan)

CRISPR-Cas13a, RNA knockdown, Firefly luciferase, EML4-ALK, cell viability