[2P-0069] Programmable RNA knockdown using CRISPR-Cas13a and therapeutic target for ALK-rearranged lung cancer

〇Mr. Saifullah¹、Sakari Matomo¹、Takeshi Suzuki^3,4、Toshifumi Tsukahara^1,2 (1.Area of Bioscience and Biotechnology, School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan、2.Division of Transdisciplinary Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi city, Ishikawa 923-1292, Japan、3.Division of Functional Genomics, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Ishikawa, Japan、4.Molecular Therapeutic Target Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kamuma-cho, Kanazawa 920-1192, Japan)

CRISPR-Cas13a、RNA knockdown、Firefly luciferase、EML4-ALK、cell viability