The Molecular Biology Society of Japan

The 43rd Annual Meeting of the Molecular Biology Society of Japan

The 43rd Annual Meeting of the Molecular Biology Society of Japan

Dec 2, 2020 - Dec 4, 2020
Online

[2P-0081] 2-OMe modification revealed that seed region of siRNA guide strand is composed of two functionally different domains

○Yoshiaki Kobayashi1, Daiki Fukuhara2, Dai Akase2, Misako Aida2, Kumiko Ui-Tei1 (1.Department of Biological Sciences, Graduate School of Science, The University of Tokyo., 2.Department of Chemistry, Graduate School of Science, Hiroshima University.)

siRNA, seed region, Off-target effect, 2'-O-methyl modification

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