The Molecular Biology Society of Japan

The 43rd Annual Meeting of the Molecular Biology Society of Japan

The 43rd Annual Meeting of the Molecular Biology Society of Japan

Dec 2, 2020 - Dec 4, 2020
Online

[2P-0082] RNA chemical modifications‚ which decrease thermodynamic stabilities‚ are useful tools to reduce off-target effects caused by siRNAs

○Seongjin An1, Yoshiaki Kobayashi2, Kohei Nomura3, Hisroshi Abe3, Kumiko Ui-Tei1,2 (1.Graduate School of Frontier Sciences, The University of Tokyo, 2.Graduate School of Science, The University of Tokyo, 3.Graduate School of Science, Nagoya University)

Inosine, Off-target effect, siRNA, RNA modification, Post-transcriptional regulation

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