[2P-0194] Leader cell specification mediated by free edge-dependent HGF-sensitization during collective cell migration

○Naoya Hino¹, Gembu Maryu², Kazuhiro Aoki², Kenta Terai³, Tsuyoshi Hirashima^3,4, Michiyuki Matsuda^1,3 (1.Lab. of Bioimaging and Cell Signaling, Grad. Sch. of Biostudies, Kyoto Univ., 2.NINS, ExCELLS/NIBB, 3.Dept. of Pathol. and Biol. of Diseases, Grad. Sch. of Med., Kyoto Univ., 4.Japan Science and Technology Agency, PRESTO)

Collective cell migration, ERK MAP kinase, HGF, FRET imaging, Cell specification