[2P-0233] Regionality of intracardiac neural crest cells with diversity and differentiation fate mechanism revealed by single cell and spatial transcriptome analysis

○Akiyasu Iwase¹, Yasunobu Uchijima¹, Daiki Seya¹, Mayuko Kida¹, Hiroki Higashiyama¹, Kazuhiro Matsui¹, Akashi Taguchi², Shogo Yamamoto³, Shiro Fukuda³, Seitaro Nomura⁴, Takahide Kohro⁵, Chisa Shukunami⁶, Masahide Seki⁷, Yutaka Suzuki⁷, Youichiro Wada², Hiroyuki Aburatani³, Yukiko Kurihara¹, Sachiko Miyagawa-Tomita^1,8, Hiroki Kurihara¹ (1.Dept. of Phys. chem. and Metab., Grad. Sch. of Med., Univ. of Tokyo, 2.Radioisotope Center, Univ. of Tokyo, 3.Genome Sci. Div., RCAST, Univ. of Tokyo, 4.Dept. of Card. Med., Grad. Sch. of Med., Univ. of Tokyo, 5. Dept. of Clin. Info., Jichi Med Univ, 6.Dept. of Mol. Bio. and Biochem., Grad. Sch. of Biomed. and Health Sci. Hiroshima Univ, 7.Dept. of. Med. Genome. Sci., Grad. Sch. of Front Sci., Univ. of Tokyo, 8.Dept. of Animal Health Tech., Yamazaki Univ. Animal Health Tech)

single cell (sc) RNA-seq, Visium spatial gene expression, Neural crest cells, heart development