The Molecular Biology Society of Japan

[2P-0233] Regionality of intracardiac neural crest cells with diversity and differentiation fate mechanism revealed by single cell and spatial transcriptome analysis

○Akiyasu Iwase1, Yasunobu Uchijima1, Daiki Seya1, Mayuko Kida1, Hiroki Higashiyama1, Kazuhiro Matsui1, Akashi Taguchi2, Shogo Yamamoto3, Shiro Fukuda3, Seitaro Nomura4, Takahide Kohro5, Chisa Shukunami6, Masahide Seki7, Yutaka Suzuki7, Youichiro Wada2, Hiroyuki Aburatani3, Yukiko Kurihara1, Sachiko Miyagawa-Tomita1,8, Hiroki Kurihara1 (1.Dept. of Phys. chem. and Metab., Grad. Sch. of Med., Univ. of Tokyo, 2.Radioisotope Center, Univ. of Tokyo, 3.Genome Sci. Div., RCAST, Univ. of Tokyo, 4.Dept. of Card. Med., Grad. Sch. of Med., Univ. of Tokyo, 5. Dept. of Clin. Info., Jichi Med Univ, 6.Dept. of Mol. Bio. and Biochem., Grad. Sch. of Biomed. and Health Sci. Hiroshima Univ, 7.Dept. of. Med. Genome. Sci., Grad. Sch. of Front Sci., Univ. of Tokyo, 8.Dept. of Animal Health Tech., Yamazaki Univ. Animal Health Tech)

single cell (sc) RNA-seq, Visium spatial gene expression, Neural crest cells, heart development

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