[2P-0266] Novel knock-in rat lines created by the Combi-CRISPR method that express Cre recombinase specifically in the central catecholaminergic neurons

○Natsuki Matsushita¹, Kayo Nishizawa², Ryoji Fukabori², Hiromi Hashimoto², Yoshio Iguchi², Shigeki Kato², Yoshiki Miyasaka³, Tomoji Mashimo⁴, kosei Takeuchi¹, Kazuto Kobayashi² (1.Aichi Med. Univ. Sch. of Med., 2.Dep. Mol. Genet., Fukushima Med. Univ., 3.Inst. Exp. Animal Sci., Osaka Univ. Grad. Sch.of Med., 4.Inst. Med. Sci., Univ. of Tokyo)

CRISPR/Cas9, knock-in rat, Cre recombinase, tyrosine hydroxylase, dopamine