HCV-induced ROS/JNK signaling pathway activates the E3 ubiquitin ligase Itch to promote the release of HCV particles via polyubiquitylation of VPS4A

○Lin Deng, Adi  Ariffianto, Chieko Matsui, Takayuki Abe, Masamichi Muramatsu, Takaji Wakita, Hideki Shibata, Masatoshi  Maki, Ikuo Shoji

[2P-0285] HCV-induced ROS/JNK signaling pathway activates the E3 ubiquitin ligase Itch to promote the release of HCV particles via polyubiquitylation of VPS4A

○Lin Deng¹, Adi Ariffianto^1,2, Chieko Matsui¹, Takayuki Abe¹, Masamichi Muramatsu³, Takaji Wakita³, Hideki Shibata⁴, Masatoshi Maki⁴, Ikuo Shoji¹ (1.Div. of Infect. Dis. Ctl., Grad. Sch. of Med., Kobe Univ. , 2.Fac. of Med. Public Health Nurs., Univ. Gadjah Mada, Yogyakarta, IDN, 3.Dept. of Virology II, National Institute of Infectious Diseases, 4.Lab. of Mol. & Cell. Regulation, Dept. of Appl. Biosci., Grad. Sch. of Bioagric. Sci., Nagaya Univ.)

HCV , ROS/JNK/Itch , VPS4

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The 43rd Annual Meeting of the Molecular Biology Society of Japan

[2P-0285] HCV-induced ROS/JNK signaling pathway activates the E3 ubiquitin ligase Itch to promote the release of HCV particles via polyubiquitylation of VPS4A

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