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[2PW-16-5] The novel anti-angiogenic mechanism of vasohibin-1 via the interfering with receptor endocytosis caused by post-translational modification of microtubules.

○Miho KOBAYASHI1,3, Ikumi Wakabayashi1,2, Yasuhiro Suzuki3,4, Kashio Fujiwara1, Masanori Nakayama5, Yasufumi Sato3,4, Tetsuro Watabe1 (1.Dept. of Biochem., Grad. Sch. of Med. and Dent. Sci., Tokyo Med. and Dent. Univ., 2.Lab. of Cardiovasc. Med., Tokyo Univ. of Pharma. and Life Sci., 3.Dept. of Vasc. Biol., IDAC, Tohoku Univ., 4.NICHe, Tohoku Univ., 5.Lab. for Cell Polar. and Organ., MPI for Heart and Lung Res.)

Angiogenesis, Post-translational modification of tubulin, VEGF-signaling, endocytosis

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