Synthetic circuits compete for intracellular resources in mammalian cells. Characterization and solution of the burden with microRNA-based circuits.

○Velia Siciliano, Mustafa  Khammash, Guy-Bart Stan

10:20 AM - 10:45 AM

[3AS-09-4] Synthetic circuits compete for intracellular resources in mammalian cells. Characterization and solution of the burden with microRNA-based circuits.

○Velia Siciliano¹, Mustafa Khammash², Guy-Bart Stan³ (1.Istituto Italiano di Tecnologia-IIT, 2.ETH Zurich, 3.Imperial College London)

Resource competition, Burden, microRNAs, incoherent feedforward loop

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The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3AS-09-4] Synthetic circuits compete for intracellular resources in mammalian cells. Characterization and solution of the burden with microRNA-based circuits.

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