[3P-0341] Targeting all transforming growth factor-β isoforms with a novel Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer

○Hitomi Takahashi¹, Kazuki Takahashi¹, Yuichi Akatsu^2,3, Katarzyna A. Podyma-Inoue¹, Takehisa Matsumoto⁴, Yasuhiro Yoshimatsu^1,5, Daizo Koinuma², Mikako Shirouzu⁴, Kohei Miyazono², Tetsuro Watabe¹ (1.Dept. Biochem., Grad. Sch. Med. Dent., Tokyo Med. & Dent. Univ., 2.Dept. Mol. Pathol., Grad. Sch Med., Tokyo Univ., 3.Pharmaceutical Research Laboratories, Nippon Kayaku, 4.RIKEN, Biosystems Dynamic Research, 5.Div. Pharmacol., Grad. Sch. Med. Dent., Nigata Univ.)

TGF-β, Fc chimeric receptor, oral squamous cell cancer, angiogenesis