Mechanism of cell death induced by MO2455 which disturbs poly (ADP-ribose) metabolism in gastric cancer NCI-N87 cells.

○Yuka Sasaki, Takae Onodera, Kenji Matsuno, Takeji Takamura, Fumiaki Koizumi, Mitsuko Masutani

[3P-0351] Mechanism of cell death induced by MO2455 which disturbs poly (ADP-ribose) metabolism in gastric cancer NCI-N87 cells.

○Yuka Sasaki^1,2, Takae Onodera^1,2, Kenji Matsuno³, Takeji Takamura⁴, Fumiaki Koizumi^1,5, Mitsuko Masutani^1,2 (1.Dept. Molecular and Genomic Biomedicine, Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Lab. Collaborative Res., Div.Cell Signaling, Natl. Cancer Ctr. Res. Inst., 3.Faculty of Engineering, Kogakuin Univ., 4.Faculty of Engineering, Kanagawa inst. of tech., 5.Div. Clin. Res. Support, Komagome Hosp.)

PARG, poly(ADP-ribose), anti-cancer agent

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The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0351] Mechanism of cell death induced by MO2455 which disturbs poly (ADP-ribose) metabolism in gastric cancer NCI-N87 cells.

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