[3P-0432] Artificial enzyme system for restoration of C-to-U in Macular mouse by using APOBEC1 deaminase

○Sonali Bhakta¹, Yuko Hino², Hiroko Kodama³, Matomo Sakari¹, Toshifumi Tsukahara¹ (1.Area of Bioscience and Biotechnology, School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomicity, Ishikawa, 923-1211, 2.Department of Pediatrics, Teikyo University School of Medicine2,, 3.General Medical Education and Research Center (G-MEC), Teikyo University3)

Genetic code, APOBEC1, guide RNA, MS2 system, Macular mouse-ATP7A