5:20 PM - 5:40 PM

[3PW-11-7] Structural basis of Notch recognition by human gamma-secretase.

○Rui Zhou¹, Guanghui Yang¹, Qiang Zhou^1,2, Xuefei Guo¹, Chuangye Yan¹, Meng Ke¹, Jianlin Lei^1,3, Yigong Shi^1,2 (1.Beijing Advan. Innovation Center for Structural Biol., Tsinghua-Peking Joint Center for Life Sci., Sch. of Life Sci., Tsinghua Univ., Beijing, China, 2.Institute of Biol., Westlake Institute for Advanced Study, Hangzhou, China., 3.Technology Center for Protein Sciences, Ministry of Education Key Laboratory of Protein Sciences, Sch. of Life Sci., Tsinghua Univ., Beijing, China.)

Notch recognition, gamma-secretase, structural basis, cryo-EM.