9:40 AM - 9:58 AM

[1AW-10-3] Nuclear rupture in a mouse model of LMNA-related cardiomyopathy causes cytoplasmic exposure of the proinflammatory signaling protein HMGB1

^○Kohta Ikegami^{1, 2, 3}, Alexis Stutzman³, Sachie Ikegami³, Omar Almakki³, Sunny Liu³, Ozanna BurnickaTurek³, Peter Pytel⁴, Ivan Moskowitz^{3, 5, 4} (1.Div of Mol Cardiovas Bio, Cincinnati Children's Hospital Med Ctr, 2.Dept of Pediatrics, Univ of Cincinnati, 3.Dept of Pediatrics, Univ of Chicago, 4.Dept of Pathology, Univ of Chicago, 5.Dept of Human Genet, Univ of Chicago)

a . Chromosome / Nuclear Body(2 . Cell)