[1LBA-069] The CDC7 inhibitor-induced replication stress inflames the aneuploid cells to sensitize immune checkpoint inhibitors

^○Tomoko Yamamori¹, Yu Jie², Yukie Kashima^{1, 3}, Kosuke Tanaka¹, Tatsunori Minamide^{1, 4}, Yumi Hakozaki¹, Shunichiro Kageyama⁵, Akito Nakamura², Lightcap Eric², Niu Huifeng², Kannan Karuppiah², Akihiro Ohashi^{1, 2} (1.Dev. of Translational Genomics, EPOC, NCC, 2.Oncology Drug Discovery Unit, TDCA, Inc., 3.Dep. of Comput. Biol. and Med. Sci., 4.Dep. of Gastroenterol. and Endoscopy, NCC Hosp. East, 5.Dep. of Radiation Oncol., NCC Hosp. East)

i . Cancer Cell(4 . Animal and Plant Physiology, and Diseases)