[1P-0032] Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and clonal evolution

^○Yusuke Matsuno^{1, 2}, Mai Hyodo^{1, 3}, Mafuka Suzuki^{1, 3}, Yosuke Tanaka⁴, Yasunori Horikoshi⁵, Yasufumi Murakami³, Hidetaka Torigoe², Hiroyuki Mano⁴, Satoshi Tashiro⁵, Kenichi Yoshioka¹ (1.Lab. Genome Stability Maint., Natl. Cancer Ctr. Res. Inst., 2.Dept. Chem., Fac. Sci., Tokyo Univ. of Sci., 3.Dept. Biol. Sci. & Technol., Tokyo Univ. of Sci., 4.Dept. Cell. Signal., Natl. Cancer Ctr. Res. Inst., 5.Dept. Cell. Biol., RIRBM, Hiroshima Univ.)

c . Recombination / Mutation / Repair(1 . Molecular)