[1P-0315] IRAK1, a shared component of Toll-like receptor/IL-1 receptor pathways, frequently overexpressed in various cancers activates Wnt/β-catenin signalling pathway via the interaction of its PPPSP motif.

^○Yasuhiro Mimura¹, Masako Inui¹, Masanori Taira², Kohei Otsubo³, Hiroki Hikasa¹ (1.Dept. of Biochem., Sch. of Med., UOEH, 2.Dep. of Life Sci., Inst. of Sci. and Eng., CHUO univ., 3.Res. Inst. for Dis. of the Chest, Grad. Sch. of Med. Sci., Univ. of Kyushu)

h . Signal Transduction (Post Translational Modification)(2 . Cell)