5:05 PM - 5:30 PM

[2PS-17-4] RNA circles with minimized immunogenicity as potent PKR inhibitors

^○ChuXiao Liu¹, SiKun Guo¹, Fang Nan², YiFeng Xu¹, Li Yang^{2, 3}, LingLing Chen^{1, 3, 4} (1.State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China., 2.CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China., 3.School of Life Science and Technology, ShanghaiTech University, 100 Haike Road, Shanghai 201210, China., 4.School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.)

f . RNA / Ribonucleoprotein(1 . Molecular)