[3P-0673] Application of chromosome engineering technology (12): Development of mice producing human antibodies with expanded diversity by replacing human IgHD sequences with chemically synthesized IgHD sequences

^○Yuko Wakasa¹, Takashi Moriwaki^{2, 3}, Satoshi Abe⁴, Yuko Yajima¹, Narumi Uno¹, Yasuhiro Kazuki^{2, 3}, Kazuma Tomizuka¹ (1.Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci., 2.Div. of Genome and Cell. Func., Grad. Sch. of Med. Sci., Tottori Univ., 3.CERC, Tottori Univ., 4.Trans Chromosomics Inc.)

b . Protein Engineering / Synthetic Biology(5 . Information / System / Technology)