4:57 PM - 5:21 PM

[3PW-13-4] Spermidine directly activates fatty acid oxidation and rejuvenizes anti-tumor immunity in aged mice

^○Kenji Chamoto¹, Muna AlHabsi^{1, 2}, Ken Matsumoto³, Norimichi Nomura⁴, Yibo Wu⁵, Baihao Zhang⁶, Yuka Nakajima¹, Kazuhiko Sonomura^{7, 8}, Rosemary Menzies¹, Yuki Sugiura⁹, Yayoi Nomura⁴, Fumihiko Matsuda⁷, So Iwata⁴, Toshihiko Ogura³, Sidonia Fagarasan^{6, 10}, Tasuku Honjo¹ (1.Dept. of Immunol. Genom., CCII, Kyoto Univ. Grad. Sch. of Med., 2.NCC, Ministry of health, Muscat, Oman, 3.Dept of Dev., Neurobio., Inst. of Dev, Aging and Cancer, Tohoku Univ., 4.Dept of Cell Bio., Grad. Sch. of Med, Kyoto Univ., 5.YCI Lab. for Next-Gen. Proteomics, Cent. for Integ. Med. Sci., RIKEN Yokohama Inst., 6.Lab. for Mucosal Imm., Cen. for Integ. Med. Sci, RIKEN Yokohama Inst., 7.Cent. for Gen. Med., Grad. Sch. of Med., Kyoto Univ., 8.Life Sci. Res. Cent., Tech. Res. Lab., Shimadzu Corp., 9.Dept of Biochem., Keio Univ. Sch. of Med., 10.Div. of Integ. High-Order Reg. Sys., CCII, Kyoto Univ. Grad. Sch. of Med.)

h . Aging(4 . Animal and Plant Physiology, and Diseases)