11:10 AM - 11:29 AM
[1AW-18-6] Deletion of CTCF sites in the SHH locus alters enhancer–promoter interactions and leads to acheiropodia
○Aki Ushiki1,2, Yichi Zhang1,2,3, Chenling Xiong1,2, Jingjing Zhao1,2, Ilias GeorgakopoulosSoares1,2, Lauren Kane4, Kirsty Jamieson2, Michael J. Bamshad5,6,7, Deborah A. Nickerson6,7, Yin Shen8,2, Laura A. Lettice4, Elizabeth Lemos SilveiraLucas9, Florence Petit10, Nadav Ahituv1,2
(1.Dept. of Bioeng. and Therapeutic Sci., UCSF, 2.Inst. for Hum. Genet., UCSF, 3.Sch. of Pharmaceutical Sci., Tsinghua University, 4.MRC Hum. Genet. Unit, Inst. of Genet. and Mol. Med., Univ. of Edinburgh, 5.Dept. of Pediatrics, Univ. of Washington, 6.Dept. of Genome Sci., Univ. of Washington, 7.Brotman-Baty Inst., 8.Dept. of Neurology, UCSF, 9.Consultorio Genetica Clinica, 10.CHU Lille, Univ. of Lille)
