The Molecular Biology Society of Japan

[1P-077] Application of chromosome engineering technology (5): Construction of top-down HAC derived from chromosome 21 in human iPS cells by megabase deletion using genome editing (CRISPR/Cas9)

Masaya Egawa1, Narumi Uno1, Hitomaru Miyamoto2, Yusuke Ohkame3, Rina Komazaki1, Yuki Ishizu1, Yusaku Okano1, Taku Yunomae1, Yasuhiro Kazuki2,3,4, Kazuma Tomizuka1 (1.Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm and Life Sci, 2.Div. of Chromo. Biomed Eng., Grad. Sch. of Med. Sci., Tottori Univ., 3.CERC, Tottori Univ., 4.Chr. Eng. Group, ExCELLS)

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